Understanding Substance Use: From Experimenting to Addiction

June 24, 2025

How substances affect the brain

Many substances (such as alcohol, cannabis, opioids, stimulants, and nicotine) affect the brain’s reward system. These substances can temporarily increase levels of dopamine, a neurotransmitter associated with pleasure and motivation. Over time this can change how the brain regulates mood, decision-making, and impulse control. With repeated use the brain can become reliant on the substance to experience those feelings, making it harder to stop even when someone wants to do so.


The Role of Experimentation

Experimentation often marks the beginning of substance use, particularly during adolescence and early adulthood. Some people try substances out of curiosity, peer influence, or as a way to manage stress, anxiety, or low mood. While not everyone who experiments will go on to develop problematic use, early use (especially during key stages of brain development) can increase vulnerability to long-term patterns of use. Recognizing and talking about experimentation early can be an important step in preventing more serious concerns down the road.


Substance Use vs. Addiction

It’s important to distinguish between substance use and substance use disorder (commonly referred to as addiction):

  • Substance use involves the occasional or regular use of a substance. This may or may not cause harm.
  • Addiction is a chronic condition where a person continues to use a substance despite experiencing negative consequences. It often includes cravings, loss of control, and physical or emotional withdrawal symptoms when not using.

Addiction can develop gradually, and the signs aren’t always immediately obvious. What begins as recreational or casual use can become habitual or compulsive over time, particularly when substances are used to cope with difficult emotions or trauma.


Common Impacts of Substance Use

Substance use can have a wide range of effects on a person’s life, depending on the substance, the frequency of use, and the reasons behind it. Some common impacts include:

  • Physical Health Concerns: Long-term use can affect the liver, heart, brain, and other vital organs. Some substances can also increase the risk of overdose or injury.
  • Mental Health Challenges: Many people who use substances also experience anxiety, depression, trauma, or other mental health concerns. Sometimes it’s difficult to know which came first, but they often reinforce each other.
  • Social and Relationship Strain: Substance use can lead to conflict in relationships, difficulties at work or school, financial problems, and isolation.
  • Legal or Safety Issues: In some cases, substance use can result in impaired driving, legal charges, or unsafe behaviours that put the person or others at risk.

The Brain Can Heal

The good news is that the brain has the ability to recover. With time, support, and the right therapeutic approach, people often find that their focus, emotions, and motivation begin to stabilize. Recovery looks different for everyone, and it often involves more than just stopping use.  It may also include developing healthier coping strategies, healing from trauma, and building a stronger sense of purpose and connection.


When to Reach Out

If you’re noticing that substance use is becoming a way to cope, or if it’s starting to impact your health, mood, or relationships, it might be time to talk to someone. Therapy can provide a confidential, non-judgmental space to better understand your relationship with substances and explore new ways forward.


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